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"An increasing attention has been called to such the problems as on drug resistance of bacteria, cross infection, or hospital infection in the recent antibiotic era. Urine from 131 patients supposed to have urinary tract infectionswere used for bacteriologic-culture and sensitivity determination for isolated icroorganisms in this study. Quantitative urine cultures in 96 cases were also performed and the following results were obtained; 1. Of a total of 171 bacterialstrains isolated by routine cultures of the urine, one hundred and thirty-three were gram-negative bacilli and remaining 41 (23.6%) were gram-positive cocci. Isolated microorganisms include Staphylococci, Klebsiella aerogenes, Pseudomonas aeruginosa, E. coli and Proteus species, in order of frequency. 2. The gram-negative bacilli showed considerable susceptibility to Kanamycin in a range of 58.1 to 90.4% and were less sensitive to Chloramphenicol and Tetracycline. Pseudomonas strains were susceptible only to Polymyxin B. and resistant to all the other antibiotics, Proteus and Klebsiella aeruginosa were resistant to all the antibiotics used in this experiment. 3. 78.3% of the bacterial strains isolatedwere resistant to more than four kinds of antibiotics. 4. Of 96 cases examined by serial quantitative urine cultures, 56 (58.3%) should more than 10 organisms per milliliter of urine and most of them were indwelling catheter."
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